As shown in Table 4 and Supplementary Table 6, initial hematuria might not be associated with renal progression (adjusted sHR, 1.25; 0.93–1.67), but TA-H (adjusted sHR, 1.35; 1.12–1.63) and CD-H (adjusted sHR, 1.17; 1.02–1.34) were independent predictors of renal progression after adjustment for age, sex, hypertension, serum albumin, eGFR, proteinuria, and use of RAAS blockers and IS agents in the competing risk regression Model C. According to the magnitude of microhematuria over time, persistent hematuria was associated with a greater risk of renal progression (P = 0.040, Figure 3A). The gene discussed is ALB; the disease is Microscopic hematuria.