PTPRH and cancer: These findings suggest a role for PTPRH in differentiation programs limiting neuroblastoma cell growth, and are consistent with the upregulation of PTPRH expression upon differentiation of other cell types (Nunes-Xavier et al., 2012; Nunes-Xavier et al., 2013), as well as with its downregulation in some cancer types (Nagano et al., 2003; Bujko et al., 2017).