BRAF and neoplasm: Figure 7D again shows that when the tumor shows upregulation of the VWA5A gene and downregulation of the TIMP1 gene, the tumor has better chemosensitivity. Stratified analysis showed that the apoptosis-related prognostic model was still a clinically and statistically significant prognostic model in patients with pMMR status, BRAF wild type, and KRAS mutation (Figures 7E–H).