The results indicated that CD4+ T cell memory resting, mast cell resting, and monocyte and NK cell infiltration significantly correlated with a high m5C score, whereas plasma cell, M0 macrophage, Treg cell, and neutrophil infiltration were significantly associated with low m5C score in ccRCC patients (Figure 8B). This evidence concerns the gene CD4 and nonpapillary renal cell carcinoma.