Among the 240 candidate genes predicted by both TargetScan and miRDB, only six genes (IGFBP1, PHGDH, PTGS2, SLC9A5, VAM21, and ZNF850) were significantly upregulated in CRC and associated with patient survival based on the CRC dataset of TCGA. The gene discussed is PHGDH; the disease is colorectal carcinoma.