Increased phosphorylated-AKT levels were observed only in +DDR2/+COLI tumours compared to −DDR2/+COLI, while no difference was seen for +DDR1b/+COLI tumours versus −DDR1b/+COLI tumours, supporting the role of AKT pathway in DDR2 signalling but not in DDR1b. The gene discussed is AKT1; the disease is neoplasm.