And the transcriptional activities of p65 and IκBα genes in infected prostate epithelial cells were significantly higher than those in uninfected cells, indicating that the NF-κB signaling pathway was involved in the occurrence of prostate cancer in the early stage of inflammation, and the activation of NF-κB was time-dependent with the stimulation of inflammation (68, 73). Here, NFKB1 is linked to prostate cancer.