To expand the applicability of GNF-7 derivatives on mtRAS cancer cells, we subsequently evaluated fourteen GNF-7 derivatives against cancer cells harboring mtRAS: H358 (KRAS-G12C), AsPC-1 (KRAS-G12D), DU-145 (KRAS-G12V), SW480 (KRAS-G12V), MDA-MB-231 (KRAS-G13D), HT-29 (KRAS-Q61L), and OCI-AML3 (NRAS-Q61L). The gene discussed is KRAS; the disease is cancer.