Despite several meta-analysis studies exploring the role of 18F-FDG PET/CT in CRC, including the diagnosis of lymph node metastasis, KRAS mutation, and prognostic value (59–61), none analyzed the association of the SUVmax with KRAS mutation, the Ki-67 index, and their prognostic value. The gene discussed is KRAS; the disease is metastatic malignant neoplasm in the lymph nodes.