While the possibility that DISC1 confers susceptibility to MMIgenerated initial excitement, it was not clear that the psychosis associatedwith the Scottish family was due to (1) nonfunctional DISC1, (2) other genesdisrupted by the translocation, (3) coprecipitation of multiple disrupted genes,or (4) altered chromatin structure. The gene discussed is DISC1; the disease is psychotic disorder.