In this study, no statistical differences in the enrolled patients' general information such as age and gender were observed (P > 0.05), the serum LP-PLA2 levels were obviously different between the severe group and the mild group, and according to the logistic regression analysis, serum LP-PLA2 had independent predictive value for AHF prognosis, demonstrating that its level was of great importance in AHF and not just in CHD and CHF. This evidence concerns the gene PLA2G7 and congestive heart failure.