In dextran sodium sulfate- (DSS-) induced experiment on mouse models of colitis, SSW attenuated histopathological injuries, recovered colonic mucosa gradually, restored colonic length, downregulated contents of IL-2, IL-7, IL-12, and IL-15, upregulated IL-10 expression, regulated the quantity and subpopulation of central memory T (Tcm) and effector memory T (Tem) cells, suppressed the activation of phosphatidylinositol 3-kinase (PI3K), protein kinase B (Akt), and T-box protein expressed in T cells (T-bet) [39]. The gene discussed is AKT1; the disease is colitis.