For example, a logistic regression analysis revealed a significant interaction between the genes ERAP1 (rs27524) and HLA-C (rs10484554) in psoriasis (p=6.95×10−6), indicating that ERAP1 SNP was effective only in individuals who had at least one copy of the HLA-C SNP risk allele (Képíró et al., 2021). The gene discussed is HLA-C; the disease is psoriasis.