They are miR-9, miR-18b, miR-32, miR-34c and miR-135a, respectively, and their potential target genes interleukin-8 (IL-8), Synaptogamin1 and insulin receptor substrate2 (IRS2) are down-regulated in polycystic ovaries (Roth et al., 2014). This evidence concerns the gene CXCL8 and polycystic ovary syndrome.