The study observed a significant association of six SNPs with AD: rs405509, rs7259620, rs769449, and rs7256173 from APOE, rs6970262 from EGFR, and rs852423 from ACTB. Despite strong LD between the SNPs of the APOE gene, we did not observe a haplotype block in the studied cohort. This evidence concerns the gene ACTB and Alzheimer disease.