TNF and neoplasm: Other researchers found that the conventional STING agonist, DMXAA, could also induce the production of inflammatory cytokines (TNFα, IFN-γ, and IL-6) and chemokines (CXCL1, CXCL2, CXCL9, and CXCL10) to promote the migration, recruitment, differentiation, and expansion of macrophages and CD8+ T cells inside the tumor.