Among the target genes of IL-6 is IL-8, a member of the C-X-C family of chemokines that plays a central role in inflammation, angiogenesis, and tumour growth, with the IL-8 receptors expressed on several cell types like neutrophils, monocytes, endothelial cells, and tumour cells (75). The gene discussed is CXCL8; the disease is neoplasm.