SERPING1 and angioedema: A commercial test based on the spontaneous amidase activity and the proenzyme activatability (69) reports a sensitivity of 80%–81% and specificity of 91%–100% for general bradykinin-mediated angioedema and a sensitivity of 74%–75% and a specificity of 91%–99% for angioedema with normal C1-INH (Kininogenase kit, KininX SAS).