GSE116390 dataset (30) was composed of four types of tumor-infiltrating CD8+ T cells, which were exhausted, memory-like, naïve, and effector memory-like (EM-like) subsets, from B16 melanoma tumor-bearing mice, and GSE123813 dataset (31) contained six types of tumor-infiltrating CD8+ T cells, which were from 11 patients with advanced basal cell carcinoma, showing higher score in the exhausted related clusters. The gene discussed is CD8A; the disease is melanoma.