RGS1 expression was significantly upregulated in multiple cancers including BRCA, cholangiocarcinoma (CHOL), esophageal carcinoma (ESCA), glioblastoma multiforme (GBM), HNSC, kidney renal clear cell carcinoma (KIRC), kidney renal papillary cell carcinoma (KIRP), LUAD, rectal carcinoma (READ), and stomach adenocarcinoma (STAD) when compared with the normal samples. The gene discussed is RGS1; the disease is carcinoma of esophagus.