RGS1 expression was significantly upregulated in multiple cancers including BRCA, cholangiocarcinoma (CHOL), esophageal carcinoma (ESCA), glioblastoma multiforme (GBM), HNSC, kidney renal clear cell carcinoma (KIRC), kidney renal papillary cell carcinoma (KIRP), LUAD, rectal carcinoma (READ), and stomach adenocarcinoma (STAD) when compared with the normal samples. This evidence concerns the gene RGS1 and cholangiocarcinoma.