IGHE and infection: Multiple cycles of infection-treatment in the viable groups included (Figure 1) first revealed static levels of parasite-specific IgE (Figure 3A) but a rapid increase of parasite-specific IgG1 in mice undergoing one or two cycles of infections when compared to naïve mice (Figure 3B) following analyses at week 15 (P1) where mice for a given scheme, say 1° or 2°, are infected at a relatively younger age than animals on the same schemes 1° and 2° in the P2 design.