However, due to the rarity of the disease, very few studies involve the characterisation of the TIME and predictive biomarkers of PDL1, but case reports have suggested positive PDL1 staining, though one study noted that though LELC tumour cells expressed abundant PDL1, tumour‐specific CD8+ TILs mostly did not express PD1 (161). This evidence concerns the gene CD274 and neoplasm.