Significantly amplified chromosome regions include 7p11.2, 9p24.1, 11q13.3 (also observed in LEL-HCC), and 12p13.2, while significantly deleted regions include 9p21.3 (CDKN2A/B), which is also commonly deleted in NPC. The gene discussed is CDKN2A; the disease is nasopharyngeal carcinoma.