GCG and type 2 diabetes mellitus: Intergroup comparisons of the incretin profile showed impaired secretion of GLP-1 and increased glucagon concentration in T2DM in all time points (the AUC GLP-1 is lower (p < 0.001), and the AUC glucagon is higher (p < 0.001) in the T2DM group, Table 1 and Supplementary Figure 1), except GLP-1 baseline secretion (p = 0.7282).