As for homozygous SNP rs246240 (g.16025167A > T/G) in the ABCC1 gene, minor allele G was associated with the onset of Grade III/IV neurological toxicity in the induction phase of childhood ALL patients with the AIEOP-BFM ALL 2000 study protocol (OR 4.61; 95% CI 1.12–19.02) (Franca et al., 2017). The gene discussed is ABCC1; the disease is acute lymphoblastic leukemia.