In addition, overexpression of CAV1 in rhabdomyosarcoma cells, the cell cycle is blocked in the G2/M phase, which is accompanied by the reduced expression of p21, p16, and cleaved caspase-3, whereas the production of catalase is increased; therefore, Cav-1 enhances DNA repair and protects against cellular senescence and apoptosis from oxidative stress (Codenotti et al., 2021). The gene discussed is CAV1; the disease is rhabdomyosarcoma.