AHR and glioblastoma: Based on the relatively high expression of AhR in highly malignant glioblastoma from the histopathology study (Gramatzki et al., 2009), we consider U87 as a representative of such high-level AhR-expressing malignant glioblastoma and emphasize the plausibility of considering rutaecarpine as a potential anti-migratory compound in the malignant glioblastoma cells with high-level AhR expression.