It has been found that the AhR signaling pathway is able to regulate the growth, migration, and invasion of tumor cells (Alexander et al., 2002; Tsai et al., 2017; Jin et al., 2020), and the activation state of AhR plays an important role in the immunotherapy of certain kinds of tumors (Liu et al., 2018; Rahul and Tracy, 2018). This evidence concerns the gene AHR and neoplasm.