BECN1 and esophageal squamous cell carcinoma: We also confirmed this in vitro, and the results showed that the effect of P. gingivalis infection and Beclin1 downregulation on the proliferation, migration and antiapoptosis of ESCC cells were consistent, while these results indicate that the P. gingivalis infection and low Beclin1 expression were associated with the development and progression of ESCC.