TP53 and colorectal carcinoma: The results showed that lncRNAs in CRC tumorigenesis participated in the regulation of the EMT/P53/PI3K-Akt/KRAS signaling pathway as well as the processes related to cell cycle and cell mitosis [23, 24], which may provide novel clues for the biological effects of lncRNAs on CRC tumorigenesis [25].