We used immunohistochemistry to evaluate the expression of the above-mentioned 14 genes (HAMP, CARD16, TRIM38, CCR5, S100A8, MSR1, S100A9, S100A4, CHI3L2, PLAU, GCH1, P2RY8, UPP1, PROS1) in glioma and normal tissues. The gene discussed is TRIM38; the disease is central nervous system cancer.