We used immunohistochemistry to evaluate the expression of the above-mentioned 14 genes (HAMP, CARD16, TRIM38, CCR5, S100A8, MSR1, S100A9, S100A4, CHI3L2, PLAU, GCH1, P2RY8, UPP1, PROS1) in glioma and normal tissues. This evidence concerns the gene UPP1 and central nervous system cancer.