Among the 14 CSGs (as shown in Figure S14B) across MHC-to-HCC, MEF-to-neuron, and mESC-to-MP datasets, it has been seen that some genes, including Polr2d, Atp6v1b2, and Cttn (Figure 4A), are involved in mouse embryonic differentiation. The gene discussed is HLA-C; the disease is hepatocellular carcinoma.