KDR and hepatocellular carcinoma: Oncogenic cell signalling pathways that are upregulated in HCC include receptor tyrosine kinases (EGFR, FGFR, c‐MET, VEGFR, etc.), Wnt/ß‐catenin, MAPK/ERK, PI3K/AKT/mTOR, and the JAK/STAT signalling pathways.68, 69, 70, 71, 72