Patients with GBMs in this series had an OS length significantly shorter than patients with IDH-mutant GBM (Hazard ratio: 0.4; 95% C.I.: 02–0.8; P = 0.0127), but not significantly different from patients with IDH-wt GBM (Hazard ratio: 1.3; 95% C.I.: 0.9–1.8; P = 0.187) (Fig. 5). Here, IDH1 is linked to glioblastoma.