Taken together, it speculated that the up-regulated circBACH2 functioned as a sponge of has-miR-944 in the cytoplasm to promote the expression and activity of HNRNPC to accelerate BC cell proliferation, and that the circBACH2/ has-miR-944/HNRNPC axis regulated BC progression via the MAPK signaling pathway (Fig. 9C). The gene discussed is HNRNPC; the disease is breast cancer.