The study by Zhang et al. [33] reported a maximum reduction of cell proliferation (46.1%) with addition of 20 μg/ml adiponectin, and Wu et al. [36] demonstrated decreased proliferation of Ishikawa and SPEC -2 endometrial cancer cells by 47 and 49.5% at 20 μg/ml of adiponectin (dose-dependent decrease, p < 0.05). The gene discussed is ADIPOQ; the disease is endometrial cancer.