HNF1A-MODY has been associated with a lower renal threshold for glucose and glucosuria [3, 29, 49, 50], which could result from insulin deficiency or be a direct effect of HNF1A through reduced renal expression of SLC5A2 (also known as SGLT2 for sodium–glucose cotransporter 2) [50, 51], a key transporter involved in tubular glucose reabsorption. The gene discussed is HNF1A; the disease is Glycosuria.