In breast cancer, GSE9893, GSE7390, GSE12276 and GSE6532 datasets revealed that the patients with up‐regulated TMPRSS2 expression had significantly poor overall survival (OS), relapse‐free survival (RFS) and distant metastasis‐free survival (DMFS) compared to patients with lower TMPRSS2 expression (Figure 6A and Table 1). The gene discussed is TMPRSS2; the disease is breast cancer.