VDR and neoplasm: Two pathways important in vitamin D signaling in the epidermis with respect to proliferation and differentiation that we believe underlie the predisposition of the Vdr null mouse to tumor formation and that are at least partially regulated by VDR in a 1,25(OH)2D‐independent fashion are the Hh and wnt/β‐catenin pathways, pathways likely not coincidentally also playing important roles in hair follicle cycling.