There is plenty of evidence showing the antagonistic or competing biological functions of nuclear factor-kappa B (NF-κB) and PPARγ in inflammation, nephrotoxicity, and myocardial ischemia–reperfusion injury (Eisele et al., 2013; Scirpo et al., 2015; Liu et al., 2016; Zhang et al., 2016). Here, PPARG is linked to myocardial ischemia.