NPPB and Patent ductus arteriosus: Elsayed et al. (76) found that BNP level in premature infants with hsPDA was negatively correlated with hemodynamic parameters of whole body blood flow at 48–72 h and was positively correlated with the pulsatility and resistance index of the middle cerebral artery and coronary artery, which reflected the physiological predictive value of BNP before symptoms of PDA.