In other cases, KLF12 expression was correlated positively with disease severity such as in colorectal cancer (Bai et al., 2021), lung cancer (Mao et al., 2020), ovarian cancer (Mak et al., 2017), and endometrial cancer (Ding et al., 2019), indicating its tumor-promoting effect. This evidence concerns the gene KLF12 and lung cancer.