The critical lectins on leukocytes that bind TAG-72-associated TACAs in CRC include Sialic Acid Recognizing Ig-like Lectins (Siglecs), the C-type lectin Macrophage Galactose-type Lectin (MGL), and Dendritic Cell-Specific ICAM-3 Grabbing Non-Integrin (DC-SIGN). This evidence concerns the gene CD209 and colorectal carcinoma.