KCNE1 and atrial fibrillation: In fact, common genetic variants (a multitude of single-nucleotide polymorphisms (SNPs)) associated with AF have been detected in genome-wide association studies (GWASs) [10–12], such as endothelial nitric oxide synthase 786 T/C, CYP11B2 rs1799998, KCNE1 G38S, and caveolin-1 rs3807989 [9, 13–15].