ZEB1 and familial pancreatic carcinoma: Furthermore, EGCG suppressed the invasion, migration, and metastasis of Panc-1 and MIA PaCa-2 pancreatic cancer cells by the inhibition of the AKT pathway and modulation of EMT markers, specifically upregulated E-cadherin and downregulated N-cadherin and the mesenchymal markers TCF8/ZEB1, β-catenin, and vimentin [146].