ID1 and non-small cell lung carcinoma: Scutellaria flavonoids, especially the three prominent representatives (baicalin, baicalein, and wogonin), inhibited Id1 through the activation of Rap1-GTP binding and the dephosphorylation of AKT and Src in A549 cells, H1299 non-small-cell lung carcinoma cells, and murine A549 xenografts [134].