AKT1 and neoplasm: Further, quercetin inhibited tumor promotion by downregulating the pro-inflammatory cytokines IL-6 and IL-10; pro-survival molecules downstream of PI3K/AKT/mTOR, Wnt/β-catenin, and STAT3 such as c-FLIPL; and molecules linked to cell proliferation, including cyclin D1 and cMyc [121].