Goals of chronic myeloid leukemia treatment are: normalization of hematopoiesis (complete hematologic response), elimination of the Ph chromosome from bone marrow cells (complete cytogenetic response) and reduction of Abelson- Breakpoint Cluster Region (BCR-ABL) transcript levels from peripheral blood and bone marrow (major molecular response) (Sawyers, 1999). Here, ABL1 is linked to chronic myelogenous leukemia, BCR-ABL1 positive.