The best drugs for the treatment of chronic myeloid leukemia are BCR-ABL tyrosine kinase (TKIs) inhibitors, including Imatinib mesylate, Gefitinib, Erlotinib, Lapatinib, Canertinib, Semaxinib, Vatalanib, Sorafenib, Leflunomide, Nilotinib, Desatinib and Ponatinib. Here, ABL1 is linked to chronic myelogenous leukemia, BCR-ABL1 positive.