CD5 and Henoch-Schoenlein purpura: In patients with IgA vasculitis that had impaired Breg function, the treatment with glucocorticoid prednisolone, promoted an increase in CD5+CD1d+, CD5+CD1d+ IL-10+, and IL-10+ B cell subsets, accompanied by an increase in the serum IL-10 concentration (Hu et al., 2016).