Some enriched pathways in SS tears include leukocyte transendothelial migration (CTSB, ITGB2, MMP9), protein-lipid complex remodeling (PSAP, PLTP, APOE, MPO) and collagen catabolic process (CST3, VIM, MMP8, TGM2, ITGB2, MMP9, CTSB) (Figure 1B, Supplementary Table S1). This evidence concerns the gene CST3 and synovial sarcoma.