In addition, for the IGROV1 cell line, TUT4/7-mediated regulation may prepare the tumor for the next stage of cancer, that is, metastasis, as cell migration, “wound healing,” and “angiogenesis” related genes are deregulated upon TUT4/7 loss (Fig. 4F; Supplemental Fig. S5G). This evidence concerns the gene TUT4 and neoplasm.