APOE and cardiovascular disorder: However, APOE4 carriership was more prevalent among COVID-19 patients treated in the intensive care unit (ICU) (p = 0.0064, OR = 2.47, 95% CI 1.25–4.89, Fisher’s exact test), and the association persisted also after matching for cardiovascular disease (p = 0.020, OR = 2.15, 95% CI 1.09 – 4.24, Fisher’s exact test).