For example, lncRNA HCG11 overexpression efficiently induced cell cycle arrest, suppressed cell proliferation, and facilitated cell apoptosis, thus inhibiting glioma progression by regulating the miR-496/cytoplasmic polyadenylation element binding protein 3 axis [34], inhibiting prostate cancer through the miR-543/PI3K/AKT signaling pathway [15], and promoting hepatocellular carcinoma progression through MAPK signaling [31]. Here, AKT1 is linked to Familial prostate cancer.