CD34 and Schnyder corneal dystrophy: This approach provides the collection of CD34+ HSPCs from patients with Transfusion-dependent β-thal (TDT) and SCD and the destruction of BCL11A gene (B-cell lymphoma 11 A), a potent silencer of the fetal hemoglobin (HbF), resulting in reactivation of the γ-globin expression [62].