After 5 days of incubation in these conditions, only 40% of cells acquired a phenotype compatible with Mo-DC, although most of the specific markers (CD209-like, CD206-like, CD1a) were more weakly expressed by these cells, compared with Mo-DC generated by culturing monocytes in the presence of the cocktail, without RA synoviocytes. This evidence concerns the gene CD1A and rheumatoid arthritis.